Webb18 jan. 2012 · We have proposed an engineered post-synapse model cell-based biosensors to investigate the effects of chemicals on ionotropic glutamate receptor (GluR), which is a focus of attention as a molecular target for clinical neural drug discovery. WebbHudspeth’s research has led to a deepened understanding of the receptor cells of the inner ear and how they contribute to hearing and hearing loss. He hopes that further investigation will indicate both the causes of and potential remedies for certain forms of human hearing impairment, an affliction that affects 10 percent of the American ...
Cells Free Full-Text The Impact of Different Types of Physical ...
Webb25 okt. 2010 · A major problem with anti-cancer drug treatment is the development of acquired multidrug resistance (MDR) of the tumor cells. Verotoxin-1 (VT-1) exerts its … Webb13 apr. 2024 · Current therapies for T-cell acute leukemia are based on risk stratification and have greatly improved the survival rate for patients, but mortality rates remain high owing to relapsed disease, therapy resistance, or treatment-related toxicities/infection. Patients with relapsed disease continue to have poor outcomes. In the past few years, … science olympiad questions for class 4
The Auditory Pathway - Structures of the Ear
WebbWhen sounds are too loud for too long, these bundles are damaged. Damaged hair cells cannot respond to sound, causing noise-induced hearing loss. Since hair cells can’t be repaired or replaced in humans, … Webb25 okt. 2010 · P-gp has been proposed as a Golgi glucosylceramide flippase that enhances neutral GSL synthesis as transfection of MDR1 increases, and inhibition of P-gp decreases neutral GSL biosynthesis in cells [ 70 ]. GCS up-regulates MDR1 expression and modulates drug resistance of cancer. Webb7 nov. 2024 · The sensory receptors for hearing are mechanoreceptors located in the cochlea of the inner ear. What receptors affect hearing? These tiny hair cells are called … science olympiad rocks and minerals list 2022