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Eif2s1鍜宔if2a

WebPaclitaxel-mediated cell death was significantly increased following loss of ISR or ATF4 expression. This sensitizing effect could be partially rescued by Trolox, a ROS scavenger. We demonstrated that the alternative initiation factor EIF2A was essential for cancer cell survival after paclitaxel-mediated ISR both in vitro and in vivo. WebJun 19, 2024 · Different intrinsic and extrinsic stress pathways including endoplasmic reticulum (ER) stress converge on the phosphorylation of eukaryotic translation initiation factor 2A (EIF2A, best known as eIF2α), which characterizes the so-called "integrated stress response". This phosphorylation event is imp …

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WebJul 16, 2024 · eIF2α Antibody (D-3) is an IgG 1 κ mouse monoclonal eIF2 alpha antibody (also designated EIF2A antibody, eIF2 alpha antibody, or EIF2S1 antibody) that detects the eIF2 alpha protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. eIF2α Antibody (D-3) is available as both the non-conjugated anti-eIF2 alpha antibody form, as … WebThese antibodies target eIF2A in Human, Mouse, Rat and Non-human primate samples. Our eIF2A polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the eIF2A antibody that fits your needs. Choose from 1 of 14 eIF2A antibodies, which have been validated in experiments with 25 publications and 60 ... teacher pgce https://hhr2.net

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WebJan 23, 2007 · EIF2S1/eIF-2-alpha is a key component of the integrated stress response (ISR), required for adaptation to various stress: phosphorylation by metabolic-stress … WebNational Center for Biotechnology Information WebEIF2S1 Modification Phospho (Ser52) Visit Supplier Website Request a Quote from Santa Cruz Biotechnology. View more details on the supplier's website ... Eukaryotic translation initiation factor 2 subunit alpha, IF2A_HUMAN. UniProt Code History P05198. Gene Synonyms EIF2S1, EIF2A, EIF2, EIF-2, EIF-2A, EIF-2alpha. View additional product ... teacherph

UniProt

Category:(ab4837) Anti-EIF2S1 (phospho S51) antibody - Abcam - CiteAb

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Eif2s1鍜宔if2a

National Center for Biotechnology Information

WebEIF2S1 Antibody (AHO0802) in ICC/IF. Immunofluorescence analysis of eIF2a was done on 70% confluent log phase A549 cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with … Web017601 B6;129- Eif2s1 tm1Rjk /J These Eif2s1 knock-out mice lack translational and transcriptional regulation in the endoplasmic reticulum. These mice maybe useful in diabetes research. 017601 - eIF2alpha[S51A] Strain Details

Eif2s1鍜宔if2a

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WebRegulation of eIF2 activity. Eukaryotic translation initiation factors ( eIF2) is a G-protein that is composed of 3 non-identical subunits, eIF2S1, eIF2S2 and eIF2S3, and catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Phosphorylation of eIF2S1 modulates ... WebOct 14, 2008 · EIF2S1 is the alpha subunit of the eIF2 translation initiation complex. Although both of these proteins function in binding initiator tRNA to the 40S ribosomal subunit, the EIF2A protein does so in a codon-dependent manner, whereas eIF2 complex requires GTP. Was initially thought to constitute the ortholog of prokaryotic IF-2 (infB) …

WebPurified anti-eIF-2A Antibody - eIF-2A was initially considered to be a eukaryotic functional counterpart of the prokaryotic translation initiation factor IF2, because it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner. WebEukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, IF2A_HUMAN. ... Gene Synonyms EIF2S1, EIF2A, EIF2, EIF-2, EIF-2A, EIF-2alpha. View additional product information. Experiments from the literature. Loading published images for this product Validations. None available. Applications ? WB.

WebMay 24, 2024 · Hello, I Really need some help. Posted about my SAB listing a few weeks ago about not showing up in search only when you entered the exact name. I pretty … WebPolyclonal Antibody for studying EIF2S1/eIF2-alpha (Ser52) phosphate. Cited in 930 publications. Validated for Western Blotting, Simple Western™. Available in 2 sizes. Highly specific and rigorously validated in-house, …

WebIF2A_HUMAN antibody; see all. Images. Western blot - Anti-EIF2S1 (phospho S51) antibody (ab131505) All lanes : Anti-EIF2S1 (phospho S51) antibody (ab131505) at 1/500 dilution Lane 1 : K562 cell extract Lane 2 : K562 cell extract treated with IFN alpha Predicted band size: 36 kDa.

WebJun 24, 2024 · In this present study, a novel ferroptosis-related 15-gene signature (RELA, ACSL3, YWHAE, EIF2S1, CISD1, DDIT4, RRM2, PANX1, TLR4, ARNTL, LPIN1, HERPUD1, NCOA4, PEBP1, and GLS2) was built. It could accurately predict the prognosis of LUAD and was related to resting mast cells and resting dendritic c … teacher phobiaWebSingle cell type. Showing cell type specific RNA data of EIF2S1 (EIF-2alpha, EIF2, EIF2A). teacher phill articleWebNov 26, 2024 · The expression of EIF2S1 was increased by WB after starvation. Experiments showed that EIF2S1 plays an important role in the invasion and metastasis of liver cancer. Conclusions: The 9-mRNA model can serve as an accurate signature to predict the prognosis of liver cancer patients, but its mechanism of action needs to be further … teacher phoneWebMar 21, 2024 · EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit Alpha) is a Protein Coding gene. Diseases associated with EIF2S1 include Vaccinia and Epiphyseal … teacher philosophy essayWeband EIF2S1 phosphorylation could also selectively inhibit the translation of proteins prone to aggregation, which has been attributed to induction of RIDD.23 Furthermore, accumulation of proteins on the ER membrane leads to activation of the tran-scription factor NFKB, which initially stimulates the expression teacher philosophy of teachingWeb13665 Ensembl ENSG00000134001 ENSMUSG00000021116 UniProt P05198 Q6ZWX6 RefSeq (mRNA) NM_004094 NM_026114 RefSeq (protein) NP_004085 NP_080390 Location (UCSC) Chr 14: 67.36 – 67.39 Mb Chr 12: 78.91 – 78.93 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Eukaryotic translation initiation factor 2 … teacher phill fceWebJun 19, 2024 · Different intrinsic and extrinsic stress pathways including endoplasmic reticulum (ER) stress converge on the phosphorylation of eukaryotic translation initiation … teacher philosophy of education