WebView our 1,2-dithiolanes products at Fisher Scientific. WebSep 2, 2024 · Figure 3. Hydrogel nanoparticles generated by the crosslinking of PEGs terminated with reduced dithiolane that can form disulfide bonds. Maleimide-tagged doxorubicin can be attached either at the surface of the gel particles ( A) or in the interior ( B) depending on the order of gel crosslinking and drug conjugation.
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A dithiolane is a sulfur heterocycle derived from cyclopentane by replacing two methylene bridges (-CH 2- units) with thioether groups. The parent compounds are 1,2-dithiolane and 1,3-dithiolane. 1,2-Dithiolanes are cyclic disulfides. Some dithiolanes are natural products that can be found in foods, such as asparagusic acid in asparagus. The 4-dimethyl… WebJan 30, 2024 · This manuscript highlights dithiolane-based hydrogel photocrosslinking as a robust method for generating adaptable hydrogels with a range of biologically … bpi pin tries exceeded
1,2-dithiolanes in chemical biology a Linear disulfide-based cellular...
WebJan 30, 2024 · Using lipoic acid as a model dithiolane, disulfide crosslinks were formed under physiological conditions, enabling cell encapsulation via an initiator-free light-induced dithiolane ring-opening photopolymerization. The resulting hydrogels allow for multiple photoinduced dynamic responses including stress relaxation, stiffening, softening, and ... WebAug 1, 2007 · α-Lipoic acid (LA) 10, 11, 12 was first isolated in 1951 and is known by a diversity of names including 1,2-dithiolane-3 pentanoic acid, 1,2-dithiolane-3 valeric acid, and thioctic acid. The naturally occurring R -enantiomer of LA is an essential cofactor in α-ketoacid dehydrogenase complexes and is known to be covalently attached to the ... gym sleeveless vest manufacturers