Daptomycin and acute kidney injury
WebAug 12, 2024 · Reported Adverse Events Thought to Be Related to Study Drugs (Vancomycin, Daptomycin or β-Lactam) eTable 6. Reported Serious Adverse Events in the Combination Therapy Group eTable 7. Occurrence of Acute Kidney Injury as Defined Using Modified Kidney Disease Improving Global Outcomes (KDIGO) Criteria eTable 8. WebMar 28, 2024 · Daptomycin is reported to cause an elevation in creatine kinase levels, although frank rhabdomyolysis is rare. An even more infrequent occurrence is the simultaneous development of acute kidney injury and drug-induced liver injury with rhabdomyolysis. Daptomycin and rifampin combination are used for synergistic …
Daptomycin and acute kidney injury
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WebDaptomycin is reported to cause an elevation in creatine kinase levels, although frank rhabdomyolysis is rare. An even more infrequent occurrence is the simultaneous … WebSep 29, 2024 · A randomized trial reported that 2.1% (11/534) of the patients who received daptomycin for SSTI had an increase in CK. At the same time, severe myopathy was …
WebDec 22, 2009 · Jan T. Kielstein, Catrin Eugbers, Stefanie M. Bode-Boeger, Jens Martens-Lobenhoffer, Hermann Haller, Christian Joukhadar, Friederike Traunmüller, Wolfgang Knitsch, Carsten Hafer, Olaf Burkhardt, Dosing of daptomycin in intensive care unit patients with acute kidney injury undergoing extended dialysis—a pharmacokinetic … WebConclusions: When administered via a continuous infusion, vancomycin is associated with a 53% reduction in the odds of acute kidney injury and a 2.6-fold higher odds of …
WebMar 7, 2024 · Daptomycin is a lipopeptide antimicrobial with activity against gram-positive organisms, including antimicrobial-resistant pathogens such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus spp . WebSep 29, 2024 · Introduction. Daptomycin is a lipopeptide antibiotic often used for the treatment of methicillin-resistant Staphylococcus aureus (MRSA). Despite its clinical utility, there have been a few reports of rhabdomyolysis related to daptomycin use [1,2].In this report, we present a case of rhabdomyolysis, severe hyperkalemia, and acute kidney …
WebDaptomycin is associated with a number of adverse effects including eosinophilic pneumonia, hypersensitivity reaction, myopathy, rhabdomyolysis, headache and transaminitis. The adverse effects of …
WebMay 20, 2024 · The aim of the study was to evaluate whether patients treated for Gram-positive cardiovascular infection with daptomycin (DAP) experienced a lower … hierarchy of infinite number setsWebOn the one hand, a RCT in which a combination regimen (daptomycin or vancomycin as the first agent plus an antistaphylococcal penicillin or cefazolin as the companion agent) was compared to monotherapy with daptomycin or vancomycin for the treatment of MRSA BSI was early terminated because of a registered increased cumulative incidence of acute ... hierarchy of ideasWebMay 23, 2024 · Brief Summary: Acute kidney injury (AKI) is a frequent complication that occurs in 15 to 25% of patients after vascular surgery, and up to 40% of patients … hierarchy of indifference curveWebPatient was admitted as a case of Daptomycin- induced rhabdomyolysis with CPK level (16687 IU/L), and acute kidney injury with electrolytes disturbance (hypercalcemia, hypokalemia, and hypomagnesemia). Daptomycin was stopped and the patient was returned to the previous Antibiotics regimen (Cloxacillin, Ciprofloxacin and Fluconazole). hierarchy of indian air force ranksWebMar 1, 2010 · In conclusion, daptomycin is a relatively new drug and is being used more frequently in hospital and intensive care practice. Severe respiratory failure can occur because of drug-induced eosinophilic … hierarchy of indian navyWebAcute interstitial nephritis (AIN) represents a frequent cause of acute kidney injury, accounting for 15-27% of renal biopsies performed because of this condition. By and large, drug-induced AIN is currently the commonest etiology of AIN, with antimicrobials and nonsteroidal anti-inflammatory drugs being the most frequent offending agents. hierarchy of indian navy ranksWebFuture research is warranted to further investigate the relationship between daptomycin use and liver injury, yet it is reasonable to monitor liver function tests at baseline and weekly thereafter along with CK levels, especially in patients requiring long … hierarchy of interventions violence