Chk1 antibody
WebCHK1 (CHEK1) is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. CHK1 can also phosphorylate p53 at Ser20 in vitro. Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by proteolysis of cyclins. WebChk1 Antibody (D-7) is a mouse monoclonal IgG 1 κ, cited in 10 publications, provided at 200 µg/ml raised against amino acids 1-476 representing full length Chk1 of human …
Chk1 antibody
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WebCHEK1 (Checkpoint kinase-1) is also named as CHK1 and belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints, DNA repair and proliferating cell nuclear antigen and … WebApr 6, 2024 · The membranes were blocked in 5% BSA for 2 h at the room temperature and immunoblotted with the primary antibodies as follows: β-actin (1:2000, RLM3121, Ruiying Biological), Phospho-Chk1 (Ser345 ...
WebChk1 is involved in cell cycle arrest when DNA damage has occurred, and it plays an important role in DNA damage checkpoint, embryonic development and tumor suppression (1). Chk1 is activated in response to replication blocks and genotoxic stress, via phosphorylation of serines 317 and 345 (2). WebAntibody: Affinity purified rabbit anti-CHK1 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB. Biological Strategies: Western Blot: Chk1 Antibody [NB100-464] - Detection of Human Chk1 by Western Blot. …
WebSee all Chk1 primary antibodies Description Rabbit polyclonal to Chk1 (phospho S317) Host species Rabbit Tested applications Suitable for: IHC-P, WB, ICC/IF more details Species reactivity Reacts with: Human Immunogen Synthetic peptide. This information is proprietary to Abcam and/or its suppliers. Positive control WebMouse anti Chk1 antibody, clone 2G1D5 recognizes Chk1 also known as cell cycle checkpoint kinase homologue 1, CHK1 or checkpoint kinase-1. Chk1, like the other checkpoint kinase Chk2, is a serine/threonine protein kinase that plays a crucial role in cell cycle control. Chk1 becomes phosphorylated and consequently activated in response to …
WebRabbit polyclonal Chk1 antibody. Validated in WB, IHC and tested in Human. Cited in 24 publication(s). Independently reviewed in 3 …
crypto most activeWebDetects human, mouse, and rat Chk1 when phosphorylated at S317 in Western blots. Does not recognize Chk1 when unphosphorylated at S317. Source Polyclonal Rabbit IgG Purification Antigen Affinity-purified Immunogen Phosphopeptide containing human Chk1 S317 site Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. crypto motorcycle valorWebBackground Information. CHEK1 (Checkpoint kinase-1) is also named as CHK1 and belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints, DNA repair and proliferating cell … crypto motorcycle moedaWebHuman Phospho-Chk1 (S345) Antibody Summary Species Reactivity Human Specificity Detects human, mouse, and rat Chk1 when phosphorylated at S345. This antibody does not recognize Chk1 when unphosphorylated at S345. Source Polyclonal Rabbit IgG Purification Antigen Affinity-purified Immunogen Phosphopeptide containing human … crypto motorcycle twitterWebMonoclonal Anti-Chk1 antibody produced in mouse is suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections), immunoprecipitation, microarray and western blot at a working concentration of 1-2 μg/mL using whole extract of cultured 293T (human embryonal kidney) cells. crypto motorcycle tokenWebProduct name Anti-Chk1 (phospho S296) antibody [EPR915] See all Chk1 primary antibodies Description Rabbit monoclonal [EPR915] to Chk1 (phospho S296) Host species Rabbit Tested applications Suitable for: WB more details Unsuitable for: ICC/IF or IHC-P Species reactivity Reacts with: Human Immunogen Synthetic peptide. crypto motorcycle poocoinWebMar 20, 2024 · CHK1, in particular, has been shown to be a central relay point for switch from a DNA damage response to an immune response, promoting the upregulation of PD-L1 expression in response to DNA damage through STAT1/3 and interferon receptor factor 1 (IRF1)-mediated transcription of PD-L1 mRNA [ 3 ]. crypto motorcycle preço